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ea0063gp233 | Anterior and Posterior Pituitary | ECE2019

Evaluation of postoperative copeptin concentration as a predictive factor of diabetes insipidus after pituitary surgery. preliminary results

Navarro-Hoyas C , Gotarredona J Serrano , Delegido-Gomez L , Alfayate R , Serrano Corredor S , Revert Marrahi P , Sanchez-Ortiga R , Alfonso A Pico

Introduction: Central diabetes insipidus (DI) is observed in up to 34% of patients undergoing pituitary surgery. Early postoperative diagnosis of DI is critical because its detection allows early treatment, reducing morbidity and hospital stay. AVP levels measurement is not commonly used to diagnose DI. As an alternative, copeptin determination has been proposed, but its usefulness has only been validated in one series.Objective: To define the threshold ...

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ea0029p1435 | Pituitary Clinical | ICEECE2012

Experience in the use of tolvaptan in patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Zamuner M. Mijares , Sanchez-Pacheco M. , Tardon , Gotarredona J. Serrano , Perez O. Moreno , Avella G. Negueruela , Vidal R. Cerezo , Ortiga R. Sanchez , Alfonso A. Pico

Introduction: Hyponatremia is the most common electrolyte disorder in hospitalized patients. SIADH is characterized by euvolemic hyponatremia with sodium and urine osmolality inappropriately high. The selective antagonist of the vasopressin V2 receptor (tolvaptan) helps to eliminate water free of solute (aquaresis), being effective in treating this condition.Objetive: Evaluate the efficacy and safety of tolvaptan in the treatment of SIADH.<p class="a...

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Endocrine Abstracts

Evaluation of postoperative copeptin concentration as a predictive factor of diabetes insipidus after pituitary surgery. preliminary results

Experience in the use of tolvaptan in patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH)

BiosciAbstracts